CORRESP

Mereo BioPharma Group plc

Fourth Floor

One Cavendish Place

London W1G 0QF

United Kingdom

October 20, 2020

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention:   

Division of Corporation Finance

Office of Life Sciences

 

Re:

Mereo BioPharma Group plc (the “Company”)

Registration Statement on Form F-3

Filed on October 6, 2020

File No. 333-249341

VIA EDGAR

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company respectfully requests that the effectiveness of the registration statement on Form F-3 (File No. 333-249341) of the Company (the “Registration Statement”) be accelerated so that the Company’s Registration Statement will become effective at 04:00 p.m., Eastern Time, on October 21, 2020 or as soon thereafter as may be practicable.

The undersigned respectfully requests that it be notified of the effectiveness of the Registration Statement by telephone call to our counsel, Mayer Brown LLP, by calling David S. Bakst at (212) 506-2551. The Company hereby authorizes Mr. Bakst to orally modify or withdraw this request for acceleration.

 

Very truly yours,
MEREO BIOPHARMA GROUP PLC
By:  

/s/ Denise Scots-Knight

Name:   Denise Scots-Knight
Title:   Chief Executive Officer

Cc: David S. Bakst

Mayer Brown LLP

Charles Sermon

Mereo BioPharma Group plc